Feeling constantly tired and sleepy is a common experience in today’s world. However, always being fatigued and lethargic is not a sign of good health. So, what illness might be causing your persistent sleepiness and fatigue?
1. What Illness Causes Persistent Sleepiness and Fatigue?
Common causes of persistent fatigue and lethargy include:
- Inadequate or Poor-Quality Sleep: Not getting enough sleep or having difficulty falling asleep.
- Unhealthy Lifestyle: Poor diet and lack of exercise.
- Stress, Depression, and Life Challenges: Such as losing a loved one or caring for a newborn.
- Hormonal Changes: Often seen during puberty, pregnancy, or menopause.
- Illnesses: Such as fever and COVID-19.
- Certain Medical Treatments and Medications: Such as chemotherapy, which can cause prolonged fatigue and sleepiness.

However, if you cannot explain why you are always tired and the condition persists without improvement, it could be a sign of an underlying health issue. Your symptoms of persistent fatigue and lethargy might indicate the cause of your exhaustion or weakness, but you should not self-diagnose. Instead, consult a doctor if you are concerned:
Symptoms and Possible Causes
Symptoms | Possible Causes |
Persistent daytime fatigue due to nighttime awakenings, loud snoring, gasping or choking during sleep | Sleep apnea |
Lack of energy, persistent fatigue, rapid heartbeat, difficulty breathing, and pale skin | Iron-deficiency anemia |
Fatigue, extreme thirst, frequent urination (especially at night), weight loss | Diabetes |
Constant fatigue, difficulty staying still, feeling anxious, restless, irritable, weak muscles | Hyperthyroidism (overactive thyroid) |
Extreme fatigue lasting at least 3 months (even daily activities become very difficult), cognitive issues such as poor thinking, memory, and concentration, flu-like symptoms | Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) |
2. How to Address Persistent Fatigue and Lethargy
If a medical condition is not causing your fatigue and sleepiness, lifestyle changes may significantly improve your symptoms:
- Practice Good Sleep Hygiene: Aim for 7-9 hours of sleep each night. Avoid caffeine, electronic devices, and exercise right before bed. Try to go to bed and wake up at the same time each day.
- Avoid Alcohol and Drugs: Refrain from using illicit drugs and limit alcohol consumption to moderate levels if necessary.

- Eat a Healthy Diet: A balanced diet and adequate hydration will help nourish your body.
- Manage Stress: Yoga, mindfulness, meditation, and regular exercise can help reduce stress and increase energy.
- Consult Your Healthcare Provider: Schedule an appointment to rule out infections, illnesses, vitamin deficiencies, and other health conditions. Discuss any medications you are taking to see if they might be causing your symptoms.
- Exercise Regularly: Regular exercise is crucial for a healthy lifestyle. Although it may seem counterintuitive, vigorous exercise can boost energy once you are accustomed to it. However, excessive exercise can cause fatigue, so consult your doctor for the best approach.
- Maintain a Healthy Weight: Discuss your ideal weight with your doctor and aim to stay within that range.
Treatment for persistent fatigue and sleepiness will depend on the underlying cause and may include:
- Talk Therapy: For example, cognitive behavioral therapy (CBT)
- Advice on Improving Sleep Quality
- Recommendations for Relaxation Techniques or Lifestyle Changes
- Referral to a Specialist: Your primary care doctor may refer you to a specialist if they cannot determine the cause of your symptoms. You might need tests such as blood work to check for anemia, diabetes, or thyroid issues.
3. Important Notes for Those Experiencing Persistent Fatigue and Sleepiness
Fatigue and lethargy can result from many conditions. If you consistently wake up feeling tired or have trouble staying awake during the day, talk to your doctor about your symptoms. They can help determine if your fatigue is a symptom of another condition and find the most appropriate treatment for you. Seek medical attention immediately if:
- You have been feeling fatigued for several weeks without relief
- Your fatigue affects your daily life
- You experience fatigue along with other symptoms, such as weight loss or mood changes, or if you snore, gasp, or choke while sleeping
Proactively addressing your persistent fatigue and sleepiness will help you find the best path to improvement, maintain your health, and live a longer life.
Sources: .nhs.uk, my.clevelandclinic.org, webmd.com
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